- The difference between prebiotic, probiotic, and postbiotics are by their benefits.
- The benefits of prebiotics are, they mainly serve as fuel, or energy, for good bacteria in your gut, probiotics. It also additionally acts as fibres which helps with digestion, increasing satiety, and improve bowel movement.
- The benefits of probiotics are, they are able to boost the body's immune system, reduce inflammation, help with digestion, and improve mood by living in your gut for the meantime. Probiotics can also be found in foods, such as yogurt, pickled veggies, and miso.
- After probiotics consume prebiotics, they would produce byproducts called postbiotics, which have different functions based by different probiotics and prebiotics used.
- The benefits of postibiotics are, they are able to help in digestion, supplying nutrients back to probiotics, as well as improving gut environment more livable for probiotics. Head over to our article to read more about postbiotics.
1.Improve mood and restore intestinal barrier
In an in-vivo test, research has been conducted to study the effect of B.longum Rosell-175 on post-heart attack depression symptoms and intestinal permeability. There were 2 groups of test subjects. The first group (Group A) were given 1 billion CFUs of our probiotic strain, 7 days before heart attack was induced. The second group (Group B) was not given any probiotic strains. After a heart attack was induced in both groups, the subjects’ depressive behaviour were observed and evaluated for 2 weeks. Group A has shown reversed depressive behaviour compared to Group B.
The bio-markers for intestinal permeability were observed during the research. Results showed that the probiotics were able to reverse high intestinal permeability that was caused by the heart attack. In conclusion, our strain was able to decrease the depressive symptoms and restore intestinal barrier integrity.
Research paper DOI: 10.1017/S0007114511005137
2.Improve immune functions
Stress on the body can cause inflammation that affects the immune system. A clinical study to observe the effect of our probiotic strain on mental status, inflammation and the intestinal barrier were done on a group of adults. The subjects were categorised into 2 groups; Group A was given probiotic strain and Group B were not given probiotic strains. In a period of 12 weeks, the subjects’ biomarkers were constantly being observed. Results showed that adults that were given probiotic strains had a lower immune-inflammatory response, reduced depressive symptoms and better intestinal barrier integrity. In conclusion, B.longum R0175 could help to improve immune functions.
Research paper DOI: 10.1186/s12937-019-0475-x
Another in vivo study has been done to observe the memory retention ability and neuroinflammatory markers. Results of the research have suggested that the management of gut microbiota with this probiotic formulation could be a promising intervention to improve neuroinflammation-associated disorders.
Research paper DOI: 10.1080/07315724.2018.1487346
3.Improve digestive function
Multiple studies have shown that our probiotic strains could help in improving digestion functions especially by enhancing the intestinal barrier functions. In a study that observed the effect of probiotics when stress is induced, results showed a significant reduction in stress-induced gastrointestinal symptoms such as abdominal pain and nausea on research subjects that are given probiotic strains. In conclusion, results suggest that our strain can provide beneficial effects on gastrointestinal symptoms and digestion functions.
Research paper DOI: 10.1016/j.nutres.2007.10.001
Based on the research done conducted by the manufacturer for B.longum R0175, subjects were given 1 billion CFUs during the trials. Results have shown that 1 billion CFUs are enough to show similar results as research that used more than 1 billion CFUs. Hence, our formulations are based on the number of CFU counts used in the scientific study.
For probiotics to be effective, they must be alive when entering the intestine. In order to improve strain survival and protection in harsh conditions (gastric acidity, compression, thermal shock), we use a microencapsulated technology called Probicap™, which is sufficient in protecting probiotics from heat 50°C for 7 hours and with a survival rate of 99% in gastric acid.